Sen. Bernie Sanders (I-Vt.) tempered his recent critiques of Hillary Clinton in an interview on Sunday, while continuing to stress his political differences with the former secretary of state.

Sanders told the Boston Globe editorial board earlier this week that "I disagree with Hillary Clinton on virtually everything," but qualified that statement in an interview on ABC's "This Week."

"Yes, we do agree on a number of issues, and by the way, on her worst day, Hillary Clinton will be an infinitely better candidate and president than the Republican candidate on his best day," he said. "But having said that, we have very significant differences, and the key difference is I see a nation in which we have a grotesque level of income and wealth inequality."

"So do I agree with Hillary Clinton on this or that issue? Of course I do," Sanders continued, after briefly chastising host George Stephanopolous for his focus on "political gossip."

"But I think on issues, for example, like Wall Street -- you know, I believe that these guys who drove our economy into the ground, destroyed so many lives," he said. "I think that at the end of the day, what we have to do is re-establish Glass-Steagall, we have to break up these huge financial institutions. That is not Hillary Clinton’s position at all. You know, I was there on the [Trans-Pacific Partnership] from way back, that was -- Hillary Clinton took a little while to get there."

Sanders also responded to attacks from his other Democratic rival, former Maryland Gov. Martin O'Malley, who recently criticized him for calling for a primary challenger to President Barack Obama in 2012. 

The senator said the idea that he'd undermined Obama was "categorically false."

"Do I have disagreements with Barack Obama?  Was I on the floor for eight and a half hours saying, no, we should not be giving any more tax breaks to the wealthy?  Do I disagree with him on TPP?  Yes, I do," he said. "But Barack Obama is a friend of mine; I think he’s been a very strong president and has taken this country under an extraordinarily difficult moment in history in a very positive way.